High Protein Chicken Zucchini Bake

Featured in: Earthy Basil Home Dinners

This satisfying high-protein bake features tender chicken breast seasoned with oregano and smoked paprika, layered with fresh zucchini slices and a creamy Greek yogurt-egg mixture. Topped with melted mozzarella and Parmesan, it delivers 48 grams of protein per serving while staying low-carb and gluten-free. The combination of seared chicken, crisp vegetables, and gooey cheese creates a comforting dish that's perfect for weeknight dinners or meal prep.

Updated on Sun, 01 Feb 2026 08:34:00 GMT
Freshly baked High Protein Chicken Zucchini Casserole featuring golden-seared chicken, tender zucchini layers, and bubbly mozzarella cheese. Save to Pinterest
Freshly baked High Protein Chicken Zucchini Casserole featuring golden-seared chicken, tender zucchini layers, and bubbly mozzarella cheese. | mossbasil.com

One weeknight after a gym session, I opened the fridge to find chicken breasts, a pile of zucchini from the farmers market, and a tub of Greek yogurt staring back at me. I was starving and craving something hearty but clean, so I started layering things into a baking dish without much of a plan. What came out of the oven that night was this golden, bubbly, protein-packed masterpiece that became my go-to whenever I needed comfort without the carb crash. Now I make it on repeat, and it never gets old.

I first served this to friends who were on a fitness kick, and they couldnt believe it was healthy. They kept asking if there was hidden pasta or breadcrumbs because it felt so indulgent. Watching them go back for seconds while I quietly smiled was one of those small kitchen wins that reminded me how good food doesnt have to be complicated. Since then, Ive made it for potlucks, Sunday meal prep sessions, and even a few skeptical family members who now ask for the recipe.

Ingredients

  • Boneless, skinless chicken breast: The lean protein base that makes this bake so satisfying, cut into bite-sized pieces so every forkful gets a bit of everything.
  • Dried oregano, smoked paprika, and garlic powder: This trio adds warmth and depth without overpowering the creamy layers, and I learned that toasting the spices with the chicken makes a huge difference.
  • Zucchini: Sliced thin, they soften just enough to meld with the chicken while keeping a slight bite, and they soak up all the savory flavors beautifully.
  • Yellow onion and garlic: Sauteed until fragrant, they form the aromatic backbone that ties the whole dish together.
  • Large eggs and Greek yogurt: Whisked together, they create a creamy, tangy custard that binds the layers and adds extra protein without feeling heavy.
  • Shredded mozzarella and Parmesan: The gooey, golden top is non-negotiable, and using part-skim mozzarella keeps it lighter while still delivering that cheese pull.
  • Olive oil: Just enough to sear the chicken and grease the dish, adding richness without drowning the flavors.
  • Fresh parsley or basil: A handful of herbs on top brightens everything up and makes it look like you put in way more effort than you did.

Instructions

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Prep the oven and dish:
Preheat your oven to 375°F and lightly grease a 9x9-inch baking dish with olive oil so nothing sticks. This step sets you up for an easy release later.
Season the chicken:
In a medium bowl, toss the chicken pieces with oregano, smoked paprika, garlic powder, salt, and black pepper until every piece is coated. The spices will bloom when they hit the hot skillet.
Sear the chicken:
Heat olive oil in a large skillet over medium-high heat and sear the chicken for 3 to 4 minutes per side until golden but not fully cooked. Remove to a plate and let the fond build up in the pan.
Saute the aromatics:
Lower the heat to medium, add the chopped onion, and cook for 3 minutes until soft and translucent. Stir in the minced garlic and cook for 30 seconds, stirring constantly so it doesnt burn.
Make the yogurt egg mixture:
In a separate bowl, whisk the eggs and Greek yogurt together until smooth and creamy. Season lightly with salt and pepper to taste.
Combine chicken with aromatics:
Return the seared chicken to the skillet and stir to coat with the onion and garlic. Remove from heat so it stops cooking.
Build the first layer:
Arrange half of the sliced zucchini in the bottom of the prepared baking dish, then spread half of the chicken-onion mixture on top. Pour half of the yogurt-egg blend evenly over everything.
Add the first cheese layer:
Sprinkle half of the mozzarella and half of the Parmesan over the yogurt mixture. This creates a cheesy middle that melts into every bite.
Repeat the layers:
Layer the remaining zucchini, chicken mixture, and yogurt-egg blend, then finish with the rest of the mozzarella and Parmesan. Press down gently so everything settles.
Bake covered then uncovered:
Cover the dish loosely with foil and bake for 20 minutes, then remove the foil and bake another 10 to 15 minutes until the cheese is bubbly and golden. The foil keeps it moist while the uncovered finish crisps the top.
Rest and garnish:
Let the bake rest for 5 minutes before slicing so the layers set and dont slide apart. Garnish with fresh parsley or basil and serve warm.
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Air fry, roast, reheat, and dehydrate meals quickly for crispy snacks and easy weeknight dinners.
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Sliced portion of High Protein Chicken Zizzle Bake served on a white plate with a fresh green salad on the side. Save to Pinterest
Sliced portion of High Protein Chicken Zizzle Bake served on a white plate with a fresh green salad on the side. | mossbasil.com

The first time I brought this to a potluck, someone asked if it was lasagna, and I realized it kind of is, just without the noodles and guilt. That moment made me see how a simple swap, zucchini for pasta, yogurt for bechamel, could turn something indulgent into something I could eat every week without thinking twice. Now it feels less like a recipe and more like a template I tweak based on whatever vegetables or spices I have lying around.

How to Store and Reheat

Let the bake cool completely, then cover tightly with foil or transfer to an airtight container and refrigerate for up to 4 days. It reheats beautifully in the microwave for 2 to 3 minutes or in a 350°F oven for 15 minutes until warmed through. I usually portion it out into meal prep containers right after it cools, so I have grab-and-go lunches that taste homemade all week long.

Swaps and Variations

If youre not a chicken person, ground turkey or even lean ground beef work just as well, just brown them in the skillet instead of searing. For a dairy-free version, swap in plant-based yogurt and cheese, though I recommend checking the labels to make sure the protein content is comparable. Adding a handful of baby spinach, diced bell peppers, or sliced mushrooms between the layers amps up the veggie count without changing the cooking time.

Serving Suggestions

This bake is filling enough to stand alone, but I love pairing it with a simple arugula salad dressed in lemon and olive oil or a side of roasted cherry tomatoes. If youre feeding a crowd or want to stretch it further, serve it over cauliflower rice or alongside a slice of crusty whole-grain bread.

  • Top with a dollop of hot sauce or a drizzle of balsamic glaze for extra flavor.
  • Pair with a crisp white wine or sparkling water with lemon for a light, refreshing contrast.
  • Pack leftovers with a handful of mixed greens for an easy lunch bowl.
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Close-up shot of the High Protein Chicken Zucchini Bake showing a creamy Greek yogurt blend and golden Parmesan topping. Save to Pinterest
Close-up shot of the High Protein Chicken Zucchini Bake showing a creamy Greek yogurt blend and golden Parmesan topping. | mossbasil.com

This dish has become my answer to the question of how to eat well without spending hours in the kitchen or sacrificing flavor. Every time I pull it out of the oven, golden and bubbling, I remember that good food is about balance, not perfection.

Frequently Asked Questions

Can I prepare this dish ahead of time?

Yes, you can assemble the entire bake up to 24 hours in advance. Cover tightly with plastic wrap and refrigerate. When ready to cook, remove from fridge 15 minutes before baking and add 5-10 minutes to the covered baking time.

What can I substitute for Greek yogurt?

Low-fat cottage cheese works excellently and adds extra protein. Sour cream is another option, though it will add more fat. For dairy-free versions, use unsweetened plant-based yogurt with similar thickness.

How do I prevent the zucchini from making the dish watery?

Slice the zucchini thinly and pat dry with paper towels before layering. You can also lightly salt the slices and let them sit for 10 minutes, then pat dry to remove excess moisture before assembling.

Can I use chicken thighs instead of breast?

Absolutely. Boneless, skinless chicken thighs will add more flavor and stay moist during baking. The protein content will be slightly lower, but the dish will be just as delicious. Adjust seasoning to taste.

How long does this keep in the refrigerator?

Store leftovers in an airtight container for up to 4 days. Reheat individual portions in the microwave for 2-3 minutes or in a 350°F oven for 15 minutes until warmed through.

Can I freeze this bake?

Yes, this freezes well for up to 3 months. Cool completely, portion into freezer-safe containers, and freeze. Thaw overnight in the refrigerator before reheating in the oven at 350°F for 20-25 minutes.

High Protein Chicken Zucchini Bake

Golden chicken and zucchini layers with Greek yogurt and melted cheese. High protein, low carb comfort food.

Prep Time
20 minutes
Time to Cook
35 minutes
Overall Time
55 minutes
Created by Aiden Coleman


Skill Level Medium

Cuisine American

Makes 4 Portions

Special Diet Info No Gluten, Reduced Carbs

What You Need

Chicken & Seasoning

01 1 pound boneless, skinless chicken breast, cut into bite-sized pieces
02 1 teaspoon dried oregano
03 1 teaspoon smoked paprika
04 ½ teaspoon garlic powder
05 ½ teaspoon salt, plus more to taste
06 Freshly ground black pepper to taste

Vegetables

01 2 medium zucchini, thinly sliced (about 4 cups)
02 1 small yellow onion, finely chopped
03 2 cloves garlic, minced

Dairy & Eggs

01 2 large eggs
02 ½ cup plain Greek yogurt
03 1 cup shredded low-fat mozzarella cheese, divided
04 2 tablespoons grated Parmesan cheese

Other

01 1 tablespoon olive oil, plus extra for greasing
02 Fresh parsley or basil for garnish (optional)

Directions

Instruction 01

Preheat Oven and Prepare Baking Dish: Preheat the oven to 375°F. Lightly grease a 9x9-inch baking dish with olive oil.

Instruction 02

Season Chicken: In a medium bowl, combine oregano, smoked paprika, garlic powder, ½ teaspoon salt, and black pepper. Toss chicken pieces in the spice mixture until well coated.

Instruction 03

Sear Chicken: Heat 1 tablespoon olive oil in a large skillet over medium-high heat. Add the seasoned chicken and sear for 3 to 4 minutes per side until golden. Remove to a plate.

Instruction 04

Sauté Aromatics: In the same skillet, reduce heat to medium. Add chopped onion and sauté for 3 minutes until softened. Add minced garlic and cook for 30 seconds, stirring constantly.

Instruction 05

Prepare Yogurt-Egg Mixture: In a separate bowl, whisk together eggs and Greek yogurt until smooth. Season lightly with salt and pepper.

Instruction 06

Combine Chicken and Aromatics: Return seared chicken to the skillet and stir to combine with the onion and garlic mixture. Remove from heat.

Instruction 07

Layer First Half: Layer half of the sliced zucchini in the prepared baking dish. Spread half of the chicken-onion mixture over the zucchini. Pour half of the yogurt-egg mixture evenly on top. Sprinkle with half of the mozzarella and half of the Parmesan.

Instruction 08

Layer Second Half: Repeat layering with remaining zucchini slices, chicken mixture, yogurt-egg mix, and finish with remaining mozzarella and Parmesan.

Instruction 09

Bake Covered: Cover the dish loosely with aluminum foil and bake for 20 minutes.

Instruction 10

Bake Uncovered: Remove foil and bake an additional 10 to 15 minutes until the cheese is melted, bubbly, and lightly golden.

Instruction 11

Rest and Serve: Let the bake rest for 5 minutes before slicing. Garnish with chopped fresh parsley or basil if desired. Serve warm.

Gear Needed

  • 9x9-inch baking dish
  • Large skillet
  • Mixing bowls
  • Whisk
  • Sharp knife
  • Cutting board
  • Measuring spoons and cups
  • Aluminum foil

Allergy Notice

Review all components for allergens and consult a healthcare provider if unsure.
  • Contains eggs
  • Contains milk and dairy products
  • If using alternative cheese or yogurt, verify labels for additional allergens

Nutrition Details (per portion)

Nutritional details are for general reference and not a replacement for professional health advice.
  • Calorie Count: 380
  • Fat content: 16 grams
  • Carbohydrates: 10 grams
  • Proteins: 48 grams